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National Organ and Tissue Transplant Organisation (NOTTO)

Aug, 2025

4 min read

Why in the News?

NOTTO has issued a new 10-point advisory that puts women and donor families first in organ allocation. This step aims to reduce the gender gap in transplants and encourage more people to donate organs in India.

Why Cover This Topic for UPSC?

  • Relevant for UPSC Prelims & Current Affairs
  • Relevant for Mains GS Paper II (Centre–state coordination in implementing Transplantation)
  • Important for Essay and Interview

About National Organ and Tissue Transplant Organisation (NOTTO)

The National Organ and Tissue Transplant Organisation (NOTTO) is the Statutory national-level body under the Directorate General of Health Services, Ministry of Health and Family Welfare.

  • The Transplantation of Human Organs and Tissues (Amendment) Act, 2011, gave NOTTO the responsibility of managing and coordinating organ & tissue donation and transplantation across the country.

Roles and Responsibilities of NOTTO

The NOTTO plays a key role in India’s transplant system, making sure organs and tissues are smoothly transferred from donors to those who need them. Here are the key functions of NOTTO:

  • Acts as the apex centre for procurement, distribution, allocation, and transplantation of human organs and tissues.
  • Maintains and publishes the National Organ and Tissue Donation and Transplantation Registry by compiling data from states and regions.
  • Develops standard operating procedures, clinical protocols, and guidelines to ensure safe and ethical transplant practices.
  • Links five Regional Organ and Tissue Transplant Organizations (ROTTOs) and 21 State Organ and Tissue Transplant Organizations (SOTTOs) for on-ground implementation.
  • Drives public education campaigns on brain-stem death, organ pledging, and donor family support to increase donation rates.
  • Facilitates “green corridors” and inter-regional transfers to minimize transit time and preserve organ viability.

Transplantation of Human Organs and Tissues Act, 1994

The Transplantation of Human Organs and Tissues Act, 1994, regulates organ and tissue donation and transplantation in India to prevent commercial dealings and ensure ethical practices.

Key Provisions:

  • Legal Framework: Defines legal conditions for removal, storage, and transplantation.
  • Authorization Committees: Establishes national and state committees to approve transplants.
  • Consent Requirements: Mandates written consent from donors or next of kin.
  • Brain-Death Certification: Recognizes brain stem death for cadaveric donation.
  • Prohibition of Commercial Trade: Bans the sale or purchase of human organs and tissues.
  • Penalties: Imposes fines and imprisonment for violations.
  • Amendment 2011: Added tissue donation, strengthened authorization processes, and expanded penalties.

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NOTTO’s 10-Point Advisory

To reduce gender imbalance and honor donor families, NOTTO’s advisory mandates:

  1. Extra allocation “points” for women on transplant waiting lists.
  2. Priority to the near relatives of deceased donors needing organs.
  3. Public felicitation and dignified funerals for deceased donors and families.
  4. Assign a unique ID to every organ donor and recipient for an audit trail.
  5. Mandatory submission of all transplant–donation data to the national digital registry.
  6. Establish permanent transplant coordinator posts in every transplant hospital.
  7. Phase-wise development of organ retrieval centres in trauma units and medical colleges.
  8. Train emergency responders and ambulance teams to spot potential deceased donors early.
  9. Appoint state-level brand ambassadors to increase organ-donation awareness.
  10. Enforce compliance through legal action under THOTA, ensuring equity and dignity.

Multiple Choice Questions

QUESTION 1

Easy

Consider the following statements with respect to the National Organ and Tissue Transplant Organisation (NOTTO):

  1. It promotes artificial organ development through biotechnology research.

  2. It operates under the Ministry of Health and Family Welfare.

  3. It was established under the Transplantation of Human Organs and Tissues Act (THOTA), 1994.

Which of the statement(s) given above is/are correct?

Impact and Key Challenges

NOTTO has helped make India’s transplant system stronger, but challenges remain in increasing donations and making sure help reaches everyone equally.

Impact

  • Enhanced Organ Utilization: Centralized allocation increased the number of successful transplants.
  • Improved Transparency: The National Registry offers real-time data on donations and transplants.
  • Inclusive Policies: Priority to women patients and donor families under the new advisory.

Challenges

  • Persistently Low Deceased Donations: Under 1 donation per million population.
  • Low Awareness: Misconceptions about brain-stem death and consent.
  • Infrastructure Gaps: Insufficient ICU beds and retrieval teams in rural areas.
  • Skill Shortages: Limited numbers of trained transplant coordinators.
  • Enforcement Variability: Inconsistent application of anti-trafficking and legal safeguards.

Also read: Tuberculosis in India: Types, Symptoms, Challenges & Elimination Strategy 2025

Brain Stem Death

Brain stem death is the permanent loss of function of the brain stem, which controls essential life functions like breathing and heartbeat.

  • The brain stem controls breathing, heartbeat, and awareness.
  • When it stops working, recovery is impossible.
  • A person cannot breathe or be conscious without life support.
  • It is irreversible, and medically/legally, death is declared.
  • Often occurs due to severe brain injury, bleeding, or lack of oxygen

Way Forward

To meet India’s growing need for organ transplants, NOTTO and its partners can:

  • Increase deceased donations by creating more state-level “green corridors” and improving ICU protocols.
  • Include transplant coordination training in medical courses across the country.
  • Use digital tools like AI matching and mobile pledge apps for quicker organ allocation.
  • Strengthen laws to prevent organ trafficking and protect donor families.
  • Work with communities, faith groups, NGOs, and youth groups to bust myths and keep donor pledges alive.

With a stronger network, better technology, and a spirit of giving, NOTTO can turn India’s transplant system into a global example of efficiency, fairness, and compassion.

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