Mains Answer Writing - 28 Feb, 2026

GS3

Indian Polity

15 marks

“Recent advances in HIV treatment have focused on targeting the viral capsid using long-acting drugs such as lenacapavir.”
Explain the significance of capsid-targeting therapies in controlling HIV infection. Also discuss the challenges of drug resistance and the role of combination therapy.

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Tips for your answer

Start with basics – Briefly explain HIV structure and why the capsid is a critical and vulnerable drug target.
Core analysis – Link lenacapavir to advantages (long-acting prevention, adherence, public health impact) + immediately add resistance issue.
Conclude smartly – Emphasize combination therapy and future antiviral research beyond HIV (broader therapeutic potential).

10.5/15

Topper’s Answer Sheet

With detailed evaluation

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