Mains Answer Writing - 28 Feb, 2026
GS3
Indian Polity
15 marks
“Recent advances in HIV treatment have focused on targeting the viral capsid using long-acting drugs such as lenacapavir.”
Explain the significance of capsid-targeting therapies in controlling HIV infection. Also discuss the challenges of drug resistance and the role of combination therapy.
Tips for your answer
- Start with basics – Briefly explain HIV structure and why the capsid is a critical and vulnerable drug target.
- Core analysis – Link lenacapavir to advantages (long-acting prevention, adherence, public health impact) + immediately add resistance issue.
- Conclude smartly – Emphasize combination therapy and future antiviral research beyond HIV (broader therapeutic potential).
More Challenges
View All- View Challenge
GS2
Indian Polity
Yesterday
The balance between transparency and privacy is a recurring constitutional challenge in India.
In the light of recent amendments to the RTI framework through the Digital Personal Data Protection law, examine whether the exemption of personal information undermines accountability of public authorities. - View Challenge
GS2
Indian Polity
26 Feb, 2026
“Changing the name of a State in India reflects the cooperative yet asymmetrical nature of Indian federalism.”
Discuss the constitutional procedure for renaming a State and examine the role played by the State Legislature and Parliament in this process. - View Challenge
GS3
Economy
25 Feb, 2026
“Asset monetisation has emerged as a critical pillar of India’s infrastructure financing strategy.”
In this context, critically examine the objectives, mechanisms and challenges of the National Monetisation Pipeline 2.0 (NMP 2.0). How can it contribute to sustainable infrastructure development while safeguarding public interest?
Master Answer Writingfor UPSC Mains
Join thousands of aspirants mastering answer writing with daily challenges, instant AI evaluation, and topper copies
