Mains Answer Writing - 8 Oct, 2025
GS3
Science & Technology
10 marks
Discuss the significance of the discovery of regulatory T cells and the FOXP3 gene in understanding peripheral immune tolerance and its implications for treating autoimmune diseases and cancer.
Tips for your answer
- Define & Explain the Concept: Begin by clearly explaining what regulatory T cells and peripheral immune tolerance are, and how the FOXP3 gene plays a role in their function. This sets the conceptual base.
- Discuss the Significance: Explain why these discoveries are important — how they help in preventing autoimmune diseases, maintaining immune balance, and shaping new medical therapies.
- Link to Applications & Challenges: Conclude by connecting their relevance to modern therapies — like cancer immunotherapy and treatment for autoimmune disorders — and mention ongoing challenges such as balancing immune activation and suppression.
More Challenges
View All- View Challenge
GS2
Indian Polity
15 Mar, 2026
“India–Canada relations are witnessing a pragmatic reset driven by strategic, economic, and energy considerations.”
Discuss the significance of the recent India–Canada agreements, particularly in the areas of nuclear energy and critical minerals cooperation. - View Challenge
GS2
Indian Polity
Yesterday
“Passive euthanasia in India reflects the evolving interpretation of the Right to Life under Article 21 of the Constitution.”
Discuss in the light of recent Supreme Court developments and the ethical concerns surrounding end-of-life decisions. - View Challenge
GS2
International Relations
13 Mar, 2026
“The Strait of Hormuz remains one of the most critical maritime chokepoints in the global energy supply chain.”
Discuss its geopolitical significance and analyse the implications of instability in the region for India’s energy security.
Master Answer Writingfor UPSC Mains
Join thousands of aspirants mastering answer writing with daily challenges, instant AI evaluation, and topper copies
