Mains Answer Writing - 3 Dec, 2025

GS3

Science & Technology

15 marks

Discuss how hypoxia-induced changes in plasma membrane lipids influence the metastatic potential of pancreatic cancer cells. What implications does this have for future cancer therapies?

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Tips for your answer

Start with the core concept – explain hypoxia and how it alters plasma membrane lipids in cancer cells.
Link changes to behaviour – briefly show how lipid modulation affects stiffness, malleability, and migration/metastasis.
End with implications – mention therapeutic targets, role of lipidome studies, and potential for precision cancer treatment.

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