QUESTION

Easy

Science & Technology

Prelims 2021

The term ‘ACE2’ is talked about in the context of

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Explanation

  • The term 'ACE2' is talked about in the context of the spread of viral diseases, particularly COVID-19.

  • ACE2 stands for Angiotensin-Converting Enzyme 2. It's a protein found on the surface of many cell types in the human body, including those in the lungs, heart, kidneys, and intestines.

  • Here's why ACE2 is significant:

    • Receptor for SARS-CoV-2: The spike protein on the surface of the SARS-CoV-2 virus, the virus that causes COVID-19, binds to the ACE2 receptor in human cells. This binding is a critical step in the process of how the virus infects cells.
    • Multiple organ infection: Since ACE2 is expressed in various organs, it provides the virus with multiple potential entry points. This can contribute to the multi-organ complications sometimes associated with COVID-19.
    • Focus of research: Understanding the interaction between the virus and ACE2 is a major area of research for scientists developing vaccines and treatments for COVID-19.

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