GS 3: Science & TechnologyGS 2: Social JusticePrelims

Paracetamol use in pregnancy not linked to autism: study, Pg7

Lancet study refutes autism link to paracetamol use during pregnancy, affirming its safety and cautioning against unnecessary avoidance.

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Key Highlights:

  • A Lancet study published on Friday refuted claims of a link between paracetamol use during pregnancy and autism in infants.
  • The study reviewed 43 clinical studies and found no evidence of increased risk of autism spectrum disorder (ASD), ADHD, or intellectual disability.
  • The review cautions against avoiding paracetamol when needed, as untreated fever or pain during pregnancy can pose risks.

Detailed Insights:

  • In September 2025, It was advised against paracetamol use during pregnancy, citing a link to neurodevelopmental issues, but this claim lacks scientific backing.
  • Paracetamol is globally recommended as the first-line treatment for pain and fever during pregnancy due to its favorable safety profile compared to alternatives like NSAIDs and opioids.
  • Untreated maternal fever can lead to complications such as miscarriage, congenital anomalies, and preterm birth, highlighting the importance of safe and accessible treatment options.
  • Major medical organizations such as the American College of Obstetricians and Gynecologists and the European Medicines Agency continue to support paracetamol use during pregnancy.

Key Concepts Involved:

  • Analgesic: A medication used to relieve pain.
  • Antipyretic: A medication used to reduce fever.
  • Autism Spectrum Disorder (ASD): A neurodevelopmental condition affecting communication and behavior.
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