GS 3: Science & TechnologyGS 2: Social JusticePrelims

Device allows UTI diagnosis after single patient visit, Pg12

iPRISM, a new point-of-care platform, enables rapid UTI diagnosis and antibiotic susceptibility testing within 90 minutes, improving treatment and stewardship.

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Key Highlights:

  • A new point-of-care platform called iPRISM has been developed to diagnose urinary tract infections (UTIs).
  • iPRISM demonstrated 81% specificity and 82% sensitivity in screening for UTIs within 75 minutes during a double-blind clinical study.
  • The platform accurately classified 100% of samples exposed to gentamicin in 30 minutes and identified ciprofloxacin resistance in 90 minutes.

Detailed Insights:

  • UTIs are common infections, and rapid diagnosis is crucial for effective treatment and to combat antimicrobial resistance.
  • iPRISM's speed allows for immediate treatment decisions, reducing the need for follow-up appointments and improving patient care.
  • The platform supports antibiotic stewardship by enabling doctors to prescribe targeted antibiotics based on susceptibility testing results.

Scientific/Technical Concepts Involved:

  • Specificity: The ability of a test to correctly identify those without the disease.
  • Sensitivity: The ability of a test to correctly identify those with the disease.
  • Antibiotic Stewardship: Efforts to reduce the overuse and misuse of antibiotics to combat antimicrobial resistance.
iPRISM

iPRISM

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